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Abstract Title:Laxative effects of triple fermented barley extracts (FBe) on loperamide （LP）诱导大鼠的便秘。
摘要来源：
bmc补体替代药物。 2019年6月21日； 19（1）：143。 EPUB 2019年6月21日。PMID： 31226979 31226979 Su-Jin Park，Dong-chan Park，Hyung-Rae Cho，Go-Woon Jung，Khawaja Muhammad Imran Bashir，Sae Kwang Ku，Jae-Suk Choi
文章隶属关系：jong-min lim
摘要问题，会导致不适并影响生活质量。这项研究旨在评估三重发酵大麦（Hordeum vulgare L.）提取物的潜在泻药作用（F是），由糖含量，酿酒酵母和Weissella cibaria产生，在洛泊酰胺（LP）诱导的Sprague-Dawley（SD）大鼠中的便秘，这是一种痉挛性便秘的动物模型。 was induced via oral treatment with LP (3 mg/kg) for 6 days 1 h before the administration of each test compound. Similarly, FBe (100, 200 and 300 mg/kg) was orally administered to rats once a day for 6 days. The changes in number, weight, and water content of fecal, motility ratio, colonic mucosa histology, and fecal mucous contents were recorded. The laxative properties of FBe were compared with those of a cathartic stimulant, sodium picosulfate. A total of 48 (8 rats in 6 groups) healthy male rats were selected and following 10 days of acclimatization.在服用第一个剂量之前的一天，收集粪便颗粒，然后从第四次给药后立即开始或持续时间为24小时。 Charcoal transfer was conducted after the sixth and final administration of the test compounds.RESULTS: In the present study, oral administration of 100-300 mg/kg of FBe exhibited promising laxative properties including intestinal charcoal transit ratio, thicknesses and mucous producing goblet cells of colonic粘膜的粘膜数量减少，结肠内腔中保留在结肠内腔中，是由胃肠道动力的增加所介导的。
结论：结论： 因此， 因此，fbe可能会充当良好的食物，并具有良好的食物，并有效地构成了良好的良好性，并具有良好的作用性，并具有良好的效果。以100 mg/kg的剂量观察到