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。。 2022年7月22日; 27(15)。 EPUB 2022 7月22日。PMID: 35897875 Kirichenko,Alexander M Markin,Irina Y Yudina,Antonina v Starodubova,Igor A Sobenin,Alexander N Orekhov 文章隶属关系:Yuliya v Markina
摘要:心血管疾病
心血管疾病与动脉粥样硬化有关。早期预防和治疗动脉粥样硬化被认为是心血管疾病治疗的重要方面。基于天然产物的制剂会影响动脉粥样硬化的主要致病步骤,因此代表了长期预防的观点关于动脉粥样硬化的发展。大量实验和临床研究表明,甘草及其生物活性化合物 - 抗炎,抗周期动物,抗氧化剂,抗动脉粥样硬化和抗植物作用的多重有益作用,这使我们可以将甘草视为一种有希望的动力学剂。 In this review, we summarized the current knowledge on the licorice anti-atherosclerotic mechanisms of action based on the results of experimental studies, including the results of the in vitro study demonstrating licorice effect on the ability of blood serum to reduce intracellular cholesterol accumulation in cultured macrophages, and presented the results of clinical studies confirming the ameliorating activity of licorice in regard to traditional cardiovascular risk factors as well as the direct甘草的抗动脉粥样硬化作用。