维生素D补充剂的习惯用途与COVID-19感染风险降低了34％显着相关

hao ma

背景： 先前的研究具有相关的维生素D补充，以较低的急性呼吸促进膜的风险。 Emerging evidence suggests that vitamin D insufficiency is related to a higher risk of coronavirus disease 2019 (COVID-19) infection.

OBJECTIVES: We aimed to investigate the prospective association between habitual use of vitamin D supplements and risk of COVID-19 infection, and assess whether such an association di根据循环和遗传预测的维生素d的不同水平。在基线（2006-2010）时测量了维生素D补充剂，循环维生素D水平和主要协变量的使用。 Genetically predicted vitamin D levels were evaluated by genetic risk score.

RESULTS: After adjustment for covariates, the habitual use of vitamin D supplements was significantly associated with a 34% lower risk of COVID-19 infection (OR, 0.66; 95% CI, 0.45-0.97; p = 0.034）。基线或遗传预测的维生素D水平循环维生素D水平与COVID-19感染的风险无关。使用维生素D补充剂与共vid-19感染的风险之间的关联并没有改变According to the different levels of circulating or genetically predicted vitamin D (P-interactions = 0.75 and 0.74, respectively).

CONCLUSIONS: Our findings suggest that habitual use of vitamin D supplements is related to a lower risk of COVID-19 infection, although we cannot rule out the possibility that the inverse关联是由于残留混杂或选择偏差所致。需要进一步的临床试验来验证这些结果。