摘要标题:
摘要摘要。
前精神病学。 2022; 13:1033816。 EPUB 2022 12月5日。PMID: 36545037 36545037 塔瓦雷斯(Tavares),安娜·塞西亚(AnaCíliade Menezesgalvão) DráulioBarrosde Araujo,Nicole Leitegalvão-Coelho
文章隶属关系:Geovan Menezes de Sousa
摘要:
介绍:mperative。 Here we report how a set of acute parameters, namely emotional (depressive symptoms), cognitive (psychedelic experience), and physiological (salivary cortisol), recorded during an ayahuasca dosing session, modulated serum brain-derived neurotrophic factor (BDNF), serum cortisol (SC), serum interleukin 6 (IL-6), plasma C-reactive protein (CRP), and salivary cortisol awakening response (CAR).
METHODS: Results were analyzed 2 days after the psychedelic intervention (ayahuasca) versus placebo in both patients with treatment-resistant depression and healthy volunteers.将这些措施作为一项随机双盲,安慰剂对照试验的一部分(= 72)。
结果: 结果表明,在剂量较高的患者中,较大的剂量症状降低了较高的SC较高SC的抑郁症状。而唾液皮质醇的变化较小Ayahuasca干预期间的水平与降低抑郁症状的临床反应较大的患者的BDNF水平较高有关。对于患者汽车,IL-6和CRP对Ayahuasca的反应以及对健康对照组和安慰剂组中对ayahuasca的所有生物标志物的响应。
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