维生素C对过敏性接触性皮炎对p-苯基二胺的影响。
摘要来源:
接触性皮肤炎。 2016 Jun; 74(6):368-72。 EPUB 2016 3月29日。PMID: 27027508“> 27027508 Poohglin Tresukosol, Mingkwan Wichaidit, John P McFadden
Article Affiliation:David A Basketter
Abstract:BACKGROUND: Hair dyes represent one of the most important causes of allergic contact dermatitis resulting from the use of cosmetic products.主要的病变化学与P-苯基二胺(PPD)的氧化产物和密切相关的物质有关。
目标: 检查是否可以检查对抗氧化剂维生素C的事先应用是否能够重新应用。e对PPD的皮肤过敏反应。 Each was tested with a range of PPD doses and PPD-containing hair dye on untreated skin and skin pretreated for 10 min with a vitamin C formulation.
RESULTS: Pretreatment of skin sites with vitamin C led to a reduction in the intensity, or even ablation, of the cutaneous与未处理的皮肤相比,在〜75%的病例中对PPD的过敏反应。