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Abstract Title:Effectiveness of Antihyperglycemic Effect of: Implication of T-Cell细胞因子。
摘要来源:
基于EVID的补体替代药物。 2017; 2017:3707046。 EPUB 2017 11月28日。PMID: 29317893 29317893 Magloire Pandoua Nekoua, Kabirou Moutairou
Article Affiliation:Rufine Fachinan
Abstract:Background/Objective: We investigate the effect of antidiabeticfruit juice on T cells differentiation, through plasmatic cytokine quantification in type 1 diabetic rats (t1d)。
方法: 通过注射五种低剂量的链链球菌,使糖尿病患者变得糖尿病n。然后,连续28天用果汁汁处理动物。 Plasmatic levels of Th1 interleukin- (IL-) 02 and interferon- (IFN-), Th2 (IL-4), and regulatory (IL-10) cytokines were determined in rats.
Results: We observed that fruit juice induced a significant decrease in blood glucose of T1D老鼠。此外,与对照动物相比,IL-2和IFN的浓度显着升高,而糖尿病大鼠IL-4和IL-10的浓度降低。有趣的是,糖尿病大鼠的果汁汁治疗后,IL-4和IL-10水平显着增加,而IL-2和IFN浓度降低,表明这些动物中有Th2表型。对果汁的植物化学分析揭示了具有抗氧化活性的化合物的单宁,类黄酮和香豆素。