链霉菌素诱导的糖尿病大鼠Musa X Paradisiaca提取物的抗糖尿病活性和HPLC-DAD-MS的化学表征。
摘要来源：
j ethnopharmacol。 2020年2月18日：112666。 EPUB 2020 2月18日。PMID： 32084552 Baviera, D B Silva, B M Marson, J A Oliveira, R G Peccinini, I K Borges, R Pontarolo
Article Affiliation:R O Vilhena
Abstract:ETHNOPHARMACOLOGICAL RELEVANCE: The Musa x paradisiaca L.花序被称为香蕉花朵或香蕉心脏，用于治疗糖尿病。of Musa x paradisiaca in streptozotocin (STZ)-induced diabetic rats and to chemically characterize the extracts.
MATERIALS AND METHODS: Standard aqueous extracts of the flowers, bracts, and their fractions were prepared and their chemical composition was determined tentatively by high-performance liquid chromatography耦合到二极管阵列检测和质谱法（HPLC-DAD-MS）。 Changes in fasting glycemia and oral glucose tolerance were evaluated in STZ-induced diabetic rats (n = 8) treated with aqueous extracts of Musa x paradisiaca (200 mg/kg) for 20 days.
RESULTS: Chemical analyses detected 21 compounds and 17 metabolites被鉴定出，其中是p-墨酸和咖啡酸的糖基化和乙酰化苯丙烷，以及糖基化的黄酮醇和花青素。经过15天的治疗后，片水提取物和Met与未处理的糖尿病组相比，糖尿病大鼠葡萄糖负荷后的毛发部分对糖尿病的特征具有显着影响。