实验大麻二醇治疗可减少1型糖尿病的早期胰腺炎症

BACKGROUND: Destruction of the insulin-producing beta cells in type 1 diabetes (T1D) is induced by invasion of immune cells引起胰腺炎症。大麻二醇（CBD）是一种源自植物的植物大麻素，大麻sativa，可降低非肥胖糖尿病（NOD）小鼠糖尿病的发生率，这是一种自发的T1D发育动物模型。在NOD小鼠中，实验性CBD处理对T1D早期胰腺炎症的影响。

方法：每周五次持续十周。通过血糖测试确认T1D诊断后，动物接受了IVM。 Leukocyte activation and functional capillary density (FCD) were quantified via IVM.

RESULTS: CBD-treated NOD mice developed T1D later and showed significantly reduced leukocyte activation and increased FCD in the pancreatic微循环。

结论： 实验性CBD治疗减少了由弹药显微镜研究的胰腺微循环中炎症标记的标记。