婴儿喂养和1型糖尿病的风险在两个大斯堪的纳维亚人出生队列中。
摘要来源:
糖尿病护理。 2017 07; 40(7):920-927。 EPUB 2017年5月9日。PMID: 28487451 28487451 KetilStørdal,Anne-Marie Nybo Andersen,KjerstiSRønningen,Geir Joner,Torild Skrivarhaug,PålRnjølstad,Steffen Husby,Lars c Stene
文章文章隶属关系: Our aim was to study the relation between the duration of full and any breastfeeding and risk of type 1 diabetes.RESEARCH DESIGN AND METHODS: We included two population-based cohorts of children followed from birth (1996-2009) to 2014 (Denmark) or 2015 (Norway).我们分析了总共155,392个孩子的数据参加挪威母亲和儿童队列研究(MOBA)和丹麦国家出生队列(DNBC)。父母报告了婴儿6个月和18个月大的饮食习惯。结果是临床1型糖尿病,可从全国儿童期糖尿病注册表中确定。 Hazard ratios (HRs) were estimated using Cox regression.
RESULTS: Type 1 diabetes was identified in 504 children during follow-up, and the incidence of type 1 diabetes per 100,000 person-years was 30.5 in the Norwegian cohort and 23.5 in the Danish cohort.与母乳喂养的儿童相比,从未母乳喂养的儿童患1型糖尿病的风险增加了两倍(HR 2.29 [95%CI 1.14-4.61],无母乳喂养与任何母乳喂养≥12个月)。但是,在母乳喂养的人中,1型糖尿病的发生率与全部母乳喂养的持续时间无关(HR每月0.99 [95%CI 0.97-1.01])和任何母乳喂养(0.97 [0.92-1.03]。但是,在母乳喂养的人中,没有证据表明延长饱满或任何母乳喂养与降低1型糖尿病风险有关。