摘要来源： Intern Med。 2014; 53（1）：13-9。 PMID： 24390522”> 24390522 Tsukamoto, Gaku Inoue, Yuichi Watanabe, Junichiro Irie, Satoru Yamada Yoshifumi Yamada OBJECTIVE: Although caloric restriction is a widely used intervention to reduce body weight and insulin resistance, many patients长期无法遵守这种饮食疗法。低碳水化合物饮食的临床有效性是接受的NTLY在英国糖尿病的职位声明和美国糖尿病协会进行的科学综述中描述。但是，对日本2型糖尿病患者的饮食干预措施的随机试验很少。 Therefore, the aim of this study was to examine the effects of a non-calorie-restricted, low-carbohydrate diet in Japanese patients unable to adhere to a calorie-restricted diet. METHODS: The enrolled patients were randomly allocated to receive a conventional calorie-restricted diet or low-carbohydrate diet.患者每两个月从注册营养师进行六个月的咨询。我们比较了两种饮食干预措施对血糖控制和代谢概况的影响。 结果： HBA1C水平从基线从基线到六个月在低碳水化合物饮食组的六个月（基线7.6±0.6±0.4±0.4±0.4±0.4±0.4±0.4±0.4±0.4％）下降。HS 7.0±0.7％，p = 0.03），但在限制卡路里组（基线7.7±0.6％，六个月7.5±1.0％，n.s.）（组间比较，p = 0.03）。 The patients in the former group also experienced improvements in their triglyceride levels, without experiencing any major adverse effects or a decline in the quality of life. CONCLUSION: Our findings suggest that a low-carbohydrate diet is effective in lowering the HbA1c and triglyceride levels in patients with type 2 diabetes who are unable to粘附于限制卡路里的饮食。