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Abstract Title:Coenzyme Q10 suppresses apoptosis of mouse pancreaticβ-cell line MIN6。
摘要来源：
糖尿病托拉伯氏症。 2018; 10：47。 EPUB 2018年6月14日。PMID： 29942356 29942356 Youhei Fujioka，Masahiko Kato，Takeshi imamura，Shin-ichi Taniguchi，Kazuhiro Yamamoto
文章隶属关系：keisuke sumi
摘要：
方法： MIN6细胞的凋亡是由0.5 µm STS STS STS STS诱导的特定周期。 The apoptosis cascade in MIN6 cells was then investigated using WST-8 assays, annexin-V staining, western blotting, and DNA degradation analysis.
Results: Sixteen hours of 0.5 μM STS treatment led to 47% cell viability, but pretreatment with 30 μM CoQ10导致76％的生存能力显着更高（p <0.01）。 COQ10还防止了磷脂酰丝氨酸从内部小叶转移到TH细胞膜的外部小叶。 CoQ10 prevented cytochrome c release from mitochondria and activation of caspase-3.
Conclusion: We concluded that CoQ10 protects pancreaticβ-cells through anti-apoptotic effects against STS treatment.