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Abstract Title:The Hypoglycemic and Renal Protection Properties of CrocinOxidative Stress-Regulated NF-κB db/db小鼠中的信号传导。
摘要来源:
前药物。 2020; 11:541。 EPUB 2020年4月30日。PMID: 32425787 32425787 Zichun Deng,Weiwei Hu,Zhiping Li,Yuxin li
文章隶属关系:ye qiu
摘要:
背景: background: 作为主要成分。 (Iridaceae)提取物,crocin- I(CR)显示出各种药理活性。这项研究的目的是研究CR在DB/DB小鼠中CR的降血糖和肾脏保护特性。
方法:用二甲双胍(MET)(100 mg/kg)和Cr(50 mg/kg)处理k龄的db/db小鼠八周。
结果:
Conclusions: The anti-diabetic and anti-diabetic nephritic effects of CR were related to its modulation of oxidative stress-mediated NF-κB信号。