Quercus ilex L.植物化学特性和药理学作用。水提取物对体外和体内胃肠道生理参数的水性提取物。
摘要来源:
。 2017年8月9日; 94:787-793。 EPUB 2017 8月9日。PMID: 288022231 Selmi, Dhekra Grami, Hichem Sebai, Mohamed Amri, Lamjed Marzouki
Article Affiliation:Kaïs Rtibi
Abstract:INTRODUCTION: Several research studies have reported on the pharmacological relevance of the medicinal plants used for treating various胃肠道疾病并控制肠道中的饮食葡萄糖摄取。
方法: 雄性大鼠研究绿色橡木橡子含量(G)OAE)在体内和体外的胃肠道生理参数上。在这方面,使用简单的测试粉(5%阿拉伯语中的木炭为10%)和蓖麻油诱导的腹泻评估了胃肠道运动和过度分泌论文。 However, the effect of GOAE on glucose absorption and homeostasis was assessed by the Ussing chamber system and oral glucose tolerance test (OGTT) measures.
RESULTS: Various doses of the Quercus ilex aqueous extract (125, 250 and 500mgkg(-1))在正常大鼠中,口服的口服产生了与肠道饮食距离的明显剂量相关抑制作用。用500mgkg(-1)获得了最高的肠道传输减少49.34%,而参考药物引起的58.33%(可乐定,1mgkg(-1))。在蓖麻油诱导的大鼠腹泻中,Q。Ilex提取物降低了排便,流体积累和电解质传输的频率。这些影响与他的降低有关肠内粘膜中细胞内介体干扰的拓扑损害和调节。此外,果阿的处理可提高葡萄糖耐量,并显着降低葡萄糖通过肠上皮的吸收(> 50%)。 Phytochemical screening revealed the presence of many bioactive natural compounds.
CONCLUSION: These results suggest that the extract was effective towards reducing diarrhea, fluid accumulation, electrolyte transport and glucose absorption, and no toxic effects of the GOAE presented on this研究。