alliment pharmiment pharmacol ther。 2010年10月; 32(7):925-33。 pmid: 20670219
摘要作者:e P Halmos,J G Muir,J S Barrett,M Deng,S J Shepherd,P r Gibson
文章隶属关系:
AIM: To identify factors associated with diarrhoea in patients receiving enteral nutrit离子特别注意配方组合。
方法: 接受肠内营养的患者的医学历史是由ICD-10-AM编码确定的,并从2003年至2008年进行了随机选择。 Formulas were classified according to osmolality, fibre and FODMAP (fermentable oligo-, di- and mono-saccharides and polyols) content.
RESULTS: Formula FODMAP levels ranged from 10.6 to 36.5 g/day.在接受肠内营养的160名患者中,有61%的患者患有腹泻。单变量分析表明,腹泻与住院时间> 21天(或4.2),肠内营养持续时间> 11天(或4.0)和抗生素使用(或2.1)有关。通过逻辑回归模型调整了影响变量后,在伊索尔斯1.5上启动的患者中,出现了腹泻风险的降低五倍以上(p = 0.029;估计或0.18)。 The only characteristic unique to this formula was its FODMAP content, being 47-71% lower than any other formula.
CONCLUSIONS: Length of stay and enteral nutrition duration independently predicted diarrhoea development, while being initiated on a lower FODMAP formula reduced the likelihood of diarrhoea.由于回顾性评估不支持因果关系,因此指出了一项研究肠道公式中FODMAP的介入研究。