摘要来源: world j胃肠道。 2014年11月14日; 20(42):15837-44。 PMID: 25400470“隶属关系: Christoph g Dietrich 摘要: 目标: 研究在抗生素治疗期间,在成本效果分析抗生素期间,在德国含有乳乳杆菌的益生菌配方的含有乳酸杆菌的效果。 class =“ sub_abstract_label”>方法: 在观察性研究中,我们分析了258的肠运动频率德国西部初级保健医院感染的患者;为107例提供了一种益生菌饮料,其中含有至少100亿张乳酸乳杆菌DN 114001 B.I.D.经济分析基于患者隔离的成本与预防益生菌的摄入。 In a second pilot study, two commercially available probiotic drinks with different Lactobacillus casei strains were directly compared in 60 patients in a randomized controlled fashion.RESULTS: In the first study, the incidence of antibiotic-associated diarrhea (AAD) was significantly reduced in the intervention group (6.5%vs 28.4%),几天内AAD的持续时间明显较短(1.7±1.1 vs 3.1±2.1)。年龄较高,肌酐和下白蛋白被确定为AAD的危险因素。氨苄青霉素是AAD率最高的抗生素(50%),益生菌组的AAD降低最大(4.2%,相对风险降低92%)。经济分析表明,在此规模的部门中,ACOST优势近60000欧元。第二项研究证实了饮料对乳酸乳杆菌DN114001的预防作用; however, there were no advantages found for the other tested probiotic drink containing Lactobacillus casei Shirota.CONCLUSION: In contrast to a drink containing Lactobacillus casei Shirota, a commercially available probiotic drink containing Lactobacillus casei DN 114001成本效益降低了抗生素治疗期间AAD的患病率。
world j胃肠道。 2014年11月14日; 20(42):15837-44。 PMID: 25400470“隶属关系: Christoph g Dietrich 摘要: 目标: 研究在抗生素治疗期间,在成本效果分析抗生素期间,在德国含有乳乳杆菌的益生菌配方的含有乳酸杆菌的效果。 class =“ sub_abstract_label”>方法: 在观察性研究中,我们分析了258的肠运动频率德国西部初级保健医院感染的患者;为107例提供了一种益生菌饮料,其中含有至少100亿张乳酸乳杆菌DN 114001 B.I.D.经济分析基于患者隔离的成本与预防益生菌的摄入。 In a second pilot study, two commercially available probiotic drinks with different Lactobacillus casei strains were directly compared in 60 patients in a randomized controlled fashion.RESULTS: In the first study, the incidence of antibiotic-associated diarrhea (AAD) was significantly reduced in the intervention group (6.5%vs 28.4%),几天内AAD的持续时间明显较短(1.7±1.1 vs 3.1±2.1)。年龄较高,肌酐和下白蛋白被确定为AAD的危险因素。氨苄青霉素是AAD率最高的抗生素(50%),益生菌组的AAD降低最大(4.2%,相对风险降低92%)。经济分析表明,在此规模的部门中,ACOST优势近60000欧元。第二项研究证实了饮料对乳酸乳杆菌DN114001的预防作用; however, there were no advantages found for the other tested probiotic drink containing Lactobacillus casei Shirota.CONCLUSION: In contrast to a drink containing Lactobacillus casei Shirota, a commercially available probiotic drink containing Lactobacillus casei DN 114001成本效益降低了抗生素治疗期间AAD的患病率。
Christoph g Dietrich
目标: 研究在抗生素治疗期间,在成本效果分析抗生素期间,在德国含有乳乳杆菌的益生菌配方的含有乳酸杆菌的效果。 class =“ sub_abstract_label”>方法: 在观察性研究中,我们分析了258的肠运动频率德国西部初级保健医院感染的患者;为107例提供了一种益生菌饮料,其中含有至少100亿张乳酸乳杆菌DN 114001 B.I.D.经济分析基于患者隔离的成本与预防益生菌的摄入。 In a second pilot study, two commercially available probiotic drinks with different Lactobacillus casei strains were directly compared in 60 patients in a randomized controlled fashion.
RESULTS: In the first study, the incidence of antibiotic-associated diarrhea (AAD) was significantly reduced in the intervention group (6.5%vs 28.4%),几天内AAD的持续时间明显较短(1.7±1.1 vs 3.1±2.1)。年龄较高,肌酐和下白蛋白被确定为AAD的危险因素。氨苄青霉素是AAD率最高的抗生素(50%),益生菌组的AAD降低最大(4.2%,相对风险降低92%)。经济分析表明,在此规模的部门中,ACOST优势近60000欧元。第二项研究证实了饮料对乳酸乳杆菌DN114001的预防作用; however, there were no advantages found for the other tested probiotic drink containing Lactobacillus casei Shirota.
CONCLUSION: In contrast to a drink containing Lactobacillus casei Shirota, a commercially available probiotic drink containing Lactobacillus casei DN 114001成本效益降低了抗生素治疗期间AAD的患病率。
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