低水平光治疗对干眼症患者的影响

Antoinette Antwi

INTRODUCTION: Low-level light therapy (LLLT) or photobiomodulation, the application of red light to the eye, is used for the treatment of dry eye.有限的研究研究了LLLT作为独立治疗的功效。该研究旨在评估LLLT对干眼症的体征和症状的影响。

方法： 这项三范围的研究招募了轻度至中度干眼的参与者。访问相距7（±3）天，所有部分每次访问时，icipant收到633 nm lllt（Eye-Light®）15分钟。 Clinical measures including first and average non-invasive keratograph tear break-up time (NIKBUT), tear meniscus height (TMH), meibomian gland (MG) loss for upper and lower eyelids, ocular surface disease index (OSDI) score, tear film lipid layer thickness, meibum quality score, Schirmers test, corneal fluorescein staining and eyelid temperature for external upper (EUL) and external lower (ELL)从治疗前后的参与者的右眼测量眼睑。

结果： 三十参与者（平均[SD]年龄：31.1 [9.5]年）完成了这项研究。用LLLT处理导致第一和平均Nikbut，TMH，泪膜脂质层厚度，OSDI评分，Schirmers测试，Meibum质量评分和眼睑温度随时间的变化（所有P <0.05）。与基线相比，TMH，撕裂膜脂质层厚度和眼睑温度S对于EUL（95％CI：6.17-7.84）和ELL（95％CI：95％CI：6.17-7.73），敏感增加了0.06 mm（95％CI：0.01-0.11），12.9 nm（95％CI：1.18-24.55）和7.0°C。 OSDI分数的降低和Schirmers测试的降低为10.2（95％CI：-15.15至-5.26）和4.4 mm（95％CI：-7.31至-1.42; All P <0.05）。 There was no significant difference in corneal fluorescein staining and MG loss after LLLT.

CONCLUSION: Low-level light therapy treatment significantly improved signs and symptoms of dry eye in the early phases of treatment, suggesting its efficacy for dry eye management.