摘要标题:
低水平的光生物调节疗法调节了营养不良肌肉中的杂种,TRPC-6和PGC-1αlevels。
摘要来源:
photobiomodul光摄影激光。 2023年8月; 41(8):389-401。 EPUB 2023年7月31日。PMID: 37527194> 37527194 Mizobuti,Guilherme Luiz da Rocha,HeloinaNathalliêmarianoda Silva,Caroline Caramano deLourenço,Adriana Pertille,Elaine Cristina Leite Pereira,Elaine Perira,Elaine Minatel
caroline covater: caroline covater (PBMT)对线粒体生物发生,线粒体呼吸系统复合物的影响以及对(MDX肌肉细胞)中(MDX肌肉)中的瞬态受体潜在规范通道(例如TRPC-1和TRPC-6)的影响(胃部肌肉细胞)和MDX MUSCLOILTIOS的(MDX肌肉细胞)和研究dystrophy (DMD).There is no successful treatment for DMD, therefore demanding search for new therapies that can improve the muscle role, the quality of life, and the survival of dystrophic patients.The dystrophic primary muscle cells received PBMT at 0.6 J and 5 J, and the dystrophic gastrocnemius muscle received PBMT at 0.6 J.The dystrophic muscle cells treated with PBMT (0.6 J和5 J)在过氧化氢(HO)产生中没有细胞毒性和显着降低水平。 We also demonstrated, for the first time, the capacity of PBMT, at a low dose (0.6 J), in reducing the TRPC-6 content and in raising the peroxisome proliferator-activated receptorγcoactivator-1α(PGC-1α) content in the dystrophic gastrocnemius muscle.PBMT modulates HOproduction, TRPC-6, and PGC-1αcontent in营养不良的肌肉。这些结果表明,激光疗法可以作为营养不良患者的辅助治疗。
发布日期 : 2023年07月31日
研究类型 : 动物研究
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