芥末根茎提取物对HR-1无毛小鼠特应特应性皮炎的症状的影响。
摘要来源:
2009年3月; 42(2):96-103。 pmid: 19436148“> 19436148 研究了芥末根茎提取物对特应性皮炎(AD)模型小鼠的影响。芥末提取物被喂给HR-1无毛小鼠,该小鼠通过特殊饮食(HR-AD饮食)产生类似AD的症状。该提取物有望减少症状。 Wasabi rhizome-containing HR-AD diet (5% and 10%) reduced the scratching behavior, and the 10% wasabi rhizome HR-AD diet significantly reduced scratching behavior on days 28, 35 and 42. Plasma components (histamine, eotaxin, IgE and thymus and activation-regulated chemokine (TARC)) were decreased in the 10% wasabi rhizome HR-AD diet.在Histopatholo中基上检查(甲苯胺蓝(T.B.),主要碱性蛋白(MBP),CD4,IL-4,IL-5,Eotaxin,eotaxin,tarc和IgE),含芥末根茎的HR-AD饮食(5%和10%)显着减少了阳性细胞的数量。这些结果表明,芥末根茎提取物改善了HR-1无毛小鼠的AD样症状。