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Abstract Title:Dose-dependent effects of evening primrose oil in children and adolescents with atopic皮肤炎。
摘要来源：
ann dermatol。 2013年8月； 25（3）：285-91。 EPUB 2013 8月13日。PMID： 24003269“> 24003269 Ahn，Hye One Kim，Chun Wook Park，Cheol Heon Lee
文章隶属关系：bo Young Chung
摘要：
背景： 先前与先前的临床初步试验的临床初步试验（Ad apopic Dermarose in Attopic Dermatiation（AD）的治疗（AD）相差不同。此外，尚未确定晚上的最佳剂量和治疗时间。n>The aim of this study is to investigate the dose-response treatment effects of evening primrose oil on clinical symptoms of AD and serum concentrations of polyunsaturated fatty acids.
METHODS: Forty AD patients were enrolled for the study and randomly divided into 2 groups: those who received evening primrose oil 160 mg daily 8周，每天两次接受320毫克傍晚的少女油8周。我们评估了所有AD患者在第0、2、4和8周的湿疹面积严重程度指数（EAI）评分。此外，我们测量了血清脂肪酸的水平，包括C16：0（C18：2N（棕榈油），C18：2N：C18：3N：3N（LINOLENIC）和C20：4（LINOLENIC）和C20：4（ARACIDONIC CALCIDONIC SPARY 结果： 血清脂肪酸水平C18：3N和C20：4在320 mg组中比160 mg组高，具有统计学意义。傍晚时期油治疗，在两组中降低了EASI分数。在320 mg组中，EAI得分的改善高于160 mg组。 There were no side effects seen in either group during the study in the 2 groups.
CONCLUSION: The results of this study suggest that the 320 mg and 160 mg groups may be equally effective in treating AD patients and show dose-dependent effects on serum fatty acid levels and EASI scores.