提取物的抗伤害感受和抗炎活性以及两种迦太基tinctorius l。
抽象来源：
j Ethnopharmacol。 2014年2月3日； 151（2）：944-50。 EPUB 2013 12月11日。PMID： 24333963 24333963 Wang, Yazhen Li, Hao Zhang
Article Affiliation:Yu Wang
Abstract:ETHNOPHARMACOLOGICAL RELEVANCE: Safflower (Carthamus tinctorius L.) has been long used both in the traditional system and folk medicine as an analgesic anti-inflammatory agent in China.该研究的目的是评估迦太基Tinctorius L.水醇提取物（He）和两种孤立的kaempferol Glycosides的抗感染性和抗炎活性。
MATERIALS AND METHODS: Antinociceptive effects of HE, kaempferol 3-O-rutinoside (K-3-R) and kaempferol 3-O-glucoside (K-3-G) were assessed in mice using the acetic acid-induced writhing test, formalin test and cinnamaldehyde test. The anti-inflammatory effects of HE, K-3-R and K-3-G were determined in two animal models: carrageenan-induced paw edema and xylene-induced ear edema.
RESULTS: The HPLC analysis showed the presence of K-3-R and K-3-G in Carthamus tinctorius L. HE (500 and 1000mg/kg) as well as K-3-R and K-3-G（150、300和600mg/kg）对He，K-3-R和K-3-G的口服治疗产生了显着的伤害感，从而显着降低了致敬反应，并降低了PAW诱导的PAW降低症状。在角膜架的两个阶段中的爪水肿ENAN引起的炎症，而K-3-G仅抑制了晚期炎症。他（400和800mg/kg）和K-3-G（200、400、800mg/kg）产生了对二甲苯诱导的耳朵水肿发育的显着剂量依赖性抑制。 K-3-R only suppressed ear edema formation at a high dose (800mg/kg).
CONCLUSIONS: These results demonstrate that Carthamus tinctorius L. extract possess remarkable antinociceptive and anti-inflammatory activities which may be due to K-3-R and K-3-G at least in part,支持植物的民俗用法治疗各种炎症和疼痛疾病。