基于营养补充剂的Ehlers-Danlos综合征的新型治疗策略。
med假设。 2005; 64(2):279-83。 pmid: 15607555“ ehlers-danlos综合征是一种罕见的疾病,包括一组相关的结缔组织疾病,是由于胶原蛋白的合成和代谢中的潜在异常而引起的。 This proposal is specifically concerned with Ehlers-Danlos syndrome classic type (formerly Types I-III), which is characterized by joint hypermobility and susceptibility to injury/arthritis, skin and vascular problems (including easy bruising, bleeding, varicose veins and poor tissue healing), cardiac mitral valve prolapse, musculo-skeletal problems (myopathy, myalgia, spinal脊柱侧弯,骨质疏松症)和对周期的敏感性鼻炎。目前没有治疗该疾病。该提案的新方面是基于:(i)越来越多的科学证据表明,营养可能是许多疾病的发病机理的主要因素,曾经被认为是仅由缺陷的基因引起的; (ii)认识到,与ehlers-danlos综合征相关的许多症状也是营养缺乏症的特征; (iii)在促进正常组织功能中,在适当组合营养补充剂组合内的协同作用。 We therefore hypothesize that the symptoms associated with Ehlers-Danlos syndrome may be successfully alleviated using a specific (and potentially synergistic) combination of nutritional supplements, comprising calcium, carnitine, coenzyme Q(10), glucosamine, magnesium, methyl sulphonyl methane, pycnogenol, silica, vitamin C, and vitamin K, at dosages which以前已证明针对其他疾病的上述症状有效Rs。
ehlers-danlos综合征是一种罕见的疾病,包括一组相关的结缔组织疾病,是由于胶原蛋白的合成和代谢中的潜在异常而引起的。 This proposal is specifically concerned with Ehlers-Danlos syndrome classic type (formerly Types I-III), which is characterized by joint hypermobility and susceptibility to injury/arthritis, skin and vascular problems (including easy bruising, bleeding, varicose veins and poor tissue healing), cardiac mitral valve prolapse, musculo-skeletal problems (myopathy, myalgia, spinal脊柱侧弯,骨质疏松症)和对周期的敏感性鼻炎。目前没有治疗该疾病。该提案的新方面是基于:(i)越来越多的科学证据表明,营养可能是许多疾病的发病机理的主要因素,曾经被认为是仅由缺陷的基因引起的; (ii)认识到,与ehlers-danlos综合征相关的许多症状也是营养缺乏症的特征; (iii)在促进正常组织功能中,在适当组合营养补充剂组合内的协同作用。 We therefore hypothesize that the symptoms associated with Ehlers-Danlos syndrome may be successfully alleviated using a specific (and potentially synergistic) combination of nutritional supplements, comprising calcium, carnitine, coenzyme Q(10), glucosamine, magnesium, methyl sulphonyl methane, pycnogenol, silica, vitamin C, and vitamin K, at dosages which以前已证明针对其他疾病的上述症状有效Rs。
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