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Abstract Title:Phytocannabinoids and epilepsy.
Abstract Source:J Clin Pharm Ther. 2015年4月; 40(2):135-43。 EPUB 2014 12月4日。PMID: 25475762 25475762
W Zuardi,J a s crippa 文章隶属关系:r g dos santos
摘要:
已知的和客观:
METHODS: Literature search using the PubMed database to identify studies on phytocannabinoids and epilepsy.
RESULTS AND DISCUSSION: Preclinical studies suggest that植物大麻素,尤其是大麻二酚和大麻素,具有有效的抗惊厥作用,这些作用是由内源性大麻素系统介导的。 Human studies are limited in number and quality, but suggest that cannabidiol has anticonvulsant effects in adult and infantile epilepsy and is well tolerated after prolonged administration.
WHAT IS NEW AND CONCLUSION: Phytocannabinoids produce anticonvulsant effects through the endocannabinoid system, with few adverse effects.大麻二醇和大麻素应在随机,对照临床试验中进行测试,尤其是在婴儿癫痫综合症中。