抽象来源： 前药物。 2023; 14：1175907。 EPUB 2023 5月18日。PMID： 37274105“> 37274105”> 37274105
这项研究的目的是获取紫红色叶（PSPL）提取物对链霉菌素（STZ）诱导的雄性Sprague-Daw的糖尿病性视网膜病（DR）的影响Ley（SD）大鼠。 In this study, rats were injected intraperitoneally with a single dose of 60 mg/kg STZ, and diabetes was confirmed on day 7. Rats were further divided into a few groups, which were then orally administered with one of the following treatments: 25 mg/kg of gliclazide (D25G), 200 mg/kg of PSPL extract (DT 200), and 400 mg/kg of PSPL extract （DT 400）。但是，给予糖尿病（DNS）的正常对照组（NS）和对照组，为正常盐水（NS）持续12周。 The results show that the treated group demonstrated a reduction in serum oral glucose tolerance test (OGTT) levels of DT 200 and DT 400, and an increase in the serum and retinal insulin levels, and restored oxidative stress markers in serum and retina on week 12. The PSPL extract exhibited protective effects in maintaining the kidney, liver, retina, and pancreas architecture in 400 mg/kg compared to the 200 mg/kg治疗的组和D25G，从而恢复糖尿病诱导的大鼠的完全透明镜片。结论Sion，400 mg/kg PSPL是雄性SD大鼠STZ诱导的DR病理学改善的最有效剂量。