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抽象来源:

int j ophthalmol。 2017; 10(4):499-506。 EPUB 2017年4月18日。PMID: 28503419“> 28503419 Ilhan

文章隶属关系:

irfan ergen

摘要:

aim: 在实验性猫酸(EAP)中比较Epi-Gallocatechin Gallate(EGCG)和EllagArt cast 方法: 二十八个spraque-dawley大鼠幼犬分为四组。除了对照组的大鼠,除了对照组的大鼠E注射皮下的亚硒酸钠在产后第九天,在10(th)至14(th)天之间诱导实验性白内障。在腹膜内分别给予50 mg/(kg·d)盐溶液,50 mg/(kg·d)EGCG和200 mg/(kg·d)EA中的大鼠。 The reduced glutathione (GSH) and malondialdehyde (MDA) levels, total antioxidant status (TAS) and total oxidant status (TOS) in lens supernatants were measured.

RESULTS: The mean cataract gradings in EGCG and EA groups were found to be significantly lower在假手术组中(p <0.001)。 The mean GSH levels and TASs in EGCG and EA groups were significantly higher than that in sham group while mean MDA levels and TOSs in EGCG and EA groups were significantly lower than that in the sham group (P<0.001).

CONCLUSION: EGCG and EA have protective effects on cataract development via抑制氧化应激。

研究类型 : 动物研究
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疾病 : 白内障,

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