在兔创伤性面部神经瘫痪模型中，胸酯和甲基促甲硅酮的组织病理学和电生理学作用。
摘要来源：
am j otolaryngol。 2016年5月24日。EPUB 2016年5月24日。PMID： 27311344“> 27311344”> 27311344 Gulzade Ozyalvacli，Elcin Hakan Terzi，Sule Aydin Turkoglu，Serpil Yildiz，Yasin Ilgaz，Sinan Seyhan，Mesut，Muharrem Dagli，Muharrem Dagli
文章附属： class="sub_abstract_label">OBJECTIVE: We aimed to determine the effects of methylprednisolone and thymoquinone on nerve healing in a traumatic facial nerve paralysis animal model.SUBJECTS AND METHODS: Twenty-four rabbits were randomly divided分为4组：第一组：对照组未接受药物，也没有创伤; II组：假小组在面部神经创伤III组后未接受药物：5mg/kg/day胸腺喹酮服用；第四组：给药1mg/kg/天甲基丙醇。在所有动物中均进行初始的电生理评估。然后将面神经的颊分支剪切成形成创伤性面部瘫痪模型。每天给药两周一次。 At the end of the second month, the electrophysiological assessments were performed and the distal part of the traumatic facial nerve were dissected and examined under light microscopy.
RESULTS: Best nerve regeneration was observed in the control and the thymoquinone groups, respectively, whereas the weakest regeneration was determined in假小组。通过组织病理学评分和电生理评估来衡量，胸腺醌和甲基促甲硅酮可显着增加神经恢复。在胸腺醌组中，due to postoperative amplitude, axon diameter and thickness of myelin sheath values were significantly further increased nerve regeneration compared to that of the methylprednisolone group and these values were close to those of the values of the control group.
CONCLUSION: Thymoquinone was slightly better than甲基强酮用于功能神经恢复。胸喹酮的神经保护作用归因于其抗氧化剂和抗炎作用。胸醌可以具有改善神经损伤的新治疗选择。