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Abstract Title:Effects of polysaccharides from Gynostemma pentaphyllum (Thunb.), Makino on物理疲劳。
摘要来源:
afr j Tradit补充替代药物。 2014; 11(3):112-7。 EPUB 2014年4月3日。PMID: 25371572 25371572 隶属关系:
shan lin-na
摘要:
背景: gynostemma pentaphyllum(thunb。)Makino已据报道具有广泛的中性雌类药物健康益处。来自乳腺癌五杆菌(PGP)的多糖已被确定为负责其生物学活性的活性成分之一。尽管PGP的许多药理学活动都受到了很多关注离子,有限的证据证明了PGP的抗毒液作用。 The purpose of this study was to investigate the effects of polysaccharides from PGP on physical fatigue.
MATERIALS AND METHOD: The rats were divided into four groups, with 10 animals per group: control (C), group, low-treated (LT), group, medium-treated (MT), group, and high-treated (HT),组。 C组接受了蒸馏水,而LT,MT和HT组获得了各种剂量的PGP(100、200、400 mg/kg·D)。 30天后,在丙烯酸塑料池中进行了强迫游泳测试,然后测量了大鼠的详尽游泳时间和一些与疲劳有关的生化参数。获得的数据表明,PGP可以延长大鼠的详尽游泳时间,并减少血液乳酸(BLA)和血尿素氮(BUN),浓度,并增加血红蛋白,肝糖原和肌肉糖原浓度。
RESULT: The data obtained showed that different doses of PGP could extend the exhaustive swimming time of the rats, as well as decrease the BLA and BUN concentrations, and increase the hemoglobin, liver glycogen and muscle glycogen concentrations, which suggests that PGP had significant anti-fatigue effects on大鼠。
结论: pgp可以用作潜在的抗fatigue剂,但需要对长期使用进行进一步研究以表明其对物理疲劳的积极影响。