氟中毒与儿童认知受损有关

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Effect of Endemic Fluorosis on Cognitive Function of School Children in Alappuzha District, Kerala: A Cross Sectional研究。

Ann Indian Acad Neurol。 2021; 24（5）：715-720。 EPUB 2020 11月6日。PMID： 35002129“> 35002129 Abdulkhayarkutty，Shaji Velayudhan Cheruvallil，prasanth sudhakaran

anjana prabhakar

认知功能障碍。尽管氟中毒是特有的，但在喀拉拉邦缺乏对其对儿童认知功能的影响的研究。

AIMS: The aim of this study was to compare the cognitive function of school children with fluorosis with that of normal children and to correlate between the severity of dental fluorosis and cognitive function.

SETTINGS AND DESIGN: Cross-sectional study, conducted in collaboration with the National Fluorosis Control Programme, among school children in Alappuzha district, Kerala.

METHODS: Children aged 8-10 years, studying in 2 lower primary schools in Alappuzha district with confirmed fluorosis were selected, and compared with healthy age- and sex-matched children from the same school.乌鸦标准的渐进式矩阵和误导数字子测验用于评估认知函数。

统计分析： 连续变量通过独立SA评估通过卡方检验的mplest和分类变量。使用Spearmans的相关性评估了牙齿氟中毒的严重程度与认知障碍等级之间的关系。

结果： 每个人中有60个儿童在氟中氧和对照组中。儿童的平均年龄为8.95±0.50。只有15％的儿童在对照组中得分I级和II级SPM等级（智力上/高于平均水平），而30％。没有氟中毒的儿童都没有得分V级（智力受损）类别，而氟中毒组为20％。对照组的平均数字跨度明显更高。发现牙齿氟中毒的严重程度与乌鸦SPM等级之间存在很强的正相关性（Spearmans相关系数= 0.740）。

结论： fluorosis与儿童的认知障碍有关。有一个位置牙齿氟中毒严重程度与认知障碍等级之间的相关性。