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Abstract Title:Low-level Light Therapy for Treatment of Diabetic Foot Ulcer: A Review of Clinical Experiences.
Abstract Source:
j药物皮肤病。 2016年7月1日; 15(7):843-8。 PMID: 27391634 Eugene Koo,Rivkah Isseroff,Jared Jagdeo
文章隶属关系:Catherine n tchanque-fossuo
摘要:
背景: background: background: diabetic tooket tooker tookers(dfu)表示大量的疾病(dm)。 DFU影响DM的四分之一患者和DFU治疗的患者有限且具有挑战性。 DFU的管理仍然是重大的医疗保健和社会经济负担(2450亿美元)。有一个宽阔的DFU的一系列晚期疗法范围是昂贵的,并且在有限的已发表研究中仅表现出最小的功效。新兴的治疗方式可改善DFU并优化伤口愈合,这是使用低水平光治疗(LLLT)。 LLLT involves the use of light in the form of low-level or low-power laser or light emitting diodes to alter biochemical pathways, which may result in changes to cell shape, cell migration, and cell signaling.
OBJECTIVE: To review published clinical experiences (case series and case reports) using LLLT for treatment of DFU, and provide evidence-based recommendations and future directions on the potential of LLLT as a therapeutic modality for DFU.
METHODS AND MATERIALS: On January 16, 2016 we searched the published literature using databases: PubMed, EMBASE, CINAHL, and Web of Science with key术语:“糖尿病脚"AND ("low level laser therapy"OR"low level light therapy"OR"LLLT"OR"light emitting diode"OR"phototherapy"OR"laser").
RESULTS: After screening of titles, abstracts and/or full-text, 7 original articles were suitable in our review. Our review包含5个病例序列和2个案例报告,这些报告评估了LLLT用于治疗DFU的情况,并且所有审查的研究表明,使用没有不良事件的LLLT对DFU进行了积极的改进,尽管限制了未来的RCT。目前的替代方案的模式是昂贵的,并且根据已发表的证据显示出有限的成功,我们设想额外的研究可能允许使用LLLT对DFU进行更强有力的建议。