姜黄提取物的壳聚糖微粒对胃肠道疾病的治疗的潜力。
摘要来源：
j Microencapsul。 2024年11月； 41（7）：547-563。 EPUB 2024 8月14日。PMID： 39140474 Suwipa Ungphaiboon，Chutha takahashi Yupanqui，Sirikan Suwannasin，Chutikan Wijukkul，Niwan Tanmanee，Teerapol Srichana
文章隶属关系：pimonsri mittraparp-artraparp-arthorn To develop turmeric extract-loaded chitosan microparticles for treating gastrointestinal disorders.
METHODS: The microparticles were prepared using a spray-drying process, optimised the characteristics by biomarker loading, and encapsulation efficiency, and assessed for bioactivities related到胃肠道al diseases.
RESULTS: The optimised microparticles were spherical, with a mean diameter of 2.11 ± 0.34 µm, a SPAN of 4.46 ± 0.68, a zeta potential of +37.6 ± 0.2 mV, loading of 15.7% w/w curcuminoids, 5.4％w/w ar-turmerone，封装效率为63.26±1.62％w/w姜黄素和43.75±1.33％W/w ar ar-turmerone。姜黄提取物的封装在6 h乘20倍时改善了释放，粘附量增加了3.6倍。微颗粒表现出高酸中和能力（1.64±0.34 mEq/g），并抑制一氧化氧化物的产生，同时维持抗氧化剂和抗菌活性的同时。