甲状腺自身免疫与成年女性痤疮的关联。
摘要来源:
j eur Acad Dermatol venereol。 2012年4月; 26(4):413-6。 EPUB 2011年4月27日。PMID: 21521376 21521376 Moustou, A Katsambas, M Alevizaki, C Antoniou
Article Affiliation:T Vergou
Abstract:BACKGROUND: During the last decades an increase has been observed regarding acne in adults and especially women.
OBJECTIVE: To evaluate the association between thyroid disorder and the presence of post-adolescent acne in adult women, comparing with healthy controls.
METHODS: 107 adult women with post-adolescent acne and 60 healthy controls were included.完整的血液计数和STC反应蛋白(CRP)以及甲状腺激素和抗体水平的Andard生物化学谱[三碘甲醇(T3),甲状腺素(T4),甲状腺刺激激素(TSH),ft3(ft3),ft3(ft4),ft4(ft4),Antithythyroglobibies antythyribirin antythyribiid(antithyryties)在痤疮和对照组的所有受试者中确定过氧化物酶抗体(抗TPO)]。还进行了甲状腺超声检查。
结果: 在统计上有显着差异(p = 0.008)在阳性抗TG抗体的普遍存在中,ACNE组和对照组为25.2%的抗TG抗体,并且具有25.2%的对照组,并且具有升高的级别。与健康对照组相比,痤疮的成年女性具有高水平的抗TG的相对风险具有统计学意义(优势比3.89,p = 0.011)。该关联独立于年龄。两者之间的TSH,FT4,FT3,T4和抗TPO的值没有显着差异组。甲状腺超声检查结果没有明显差异。 Although there was no significant difference between cases and controls regarding CRP levels, it is interesting that we observed a significant elevation in CRP in those acne patients who had positive antithyroglobulin antibodies.
CONCLUSIONS: It is likely that thyroid autoimmunity might be more frequent in the adult acne patients and this should be在筛查后青春期后痤疮时要记住。