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摘要来源：
脂质健康疾病。 2018年3月27日； 17（1）：59。 EPUB 2018 3月27日。PMID： 29587770 2958770 Dehghan, Siroos Tajmiri
Article Affiliation:Mahdieh Abbasalizad Farhangi
Abstract:BACKGROUND: Hashimotos thyroiditis is associated with serious alterations in serum lipids and glucose homeostasis.当前研究的目的是评估Nigella sativa粉对血清脂质，葡萄糖稳态和anthropometric variables in patients with Hashimotos thyroiditis.
METHODS: Forty patients with Hashimotos thyroiditis, aged between 22 and 50 years old, participated in the trial and were randomly allocated into two groups of intervention and control receiving powdered Nigella sativa or placebo daily for 8周。在基线和干预后评估血清脂质，葡萄糖稳态和人体测量变量。
结果： 用nigella Sativ进行处理可显着降低体重和体重指数（BMI）。 8周后，Nigella Sativa治疗组的低密度脂蛋白胆固醇（LDL）和甘油三酸酯（TG）也降低。虽然血清高密度脂蛋白胆固醇（HDL）在用nigella sativa处理后显着增加（p <0.05）。在安慰剂治疗组中未观察到这些变化。血清NESFATIN-1浓度与血清甘油三酸酯（Tg）（r = -0.31，p = 0.04）。 thyroiditis, this medicinal plant could be considered as a beneficial herbal supplement alongside with the disease- specific medications including Levothyroxine in management of Hashimotos thyroiditis- related metabolic abnormalities.
TRIAL REGISTRATION: Iranian registry of clinical trials (registration number IRCT2014090819082N2-注册2014-09-29）。