单击此处阅读完整的文章。 Zaghloul：AndStudy。
摘要来源：
Pharm Biol。 2023年12月; 61（1）：657-665。 PMID： 37092359“> 37092359 El-Sayed M Marwan，Saleh El-Sharkawy，Mona El-Neketi
文章隶属关系：nada elhefni
摘要：
上下文：上下文： 日期浪费在大量的范围内堆积了批评和批评性的批评，问题。
目标： 日期棕榈树，linn cv zaghloul（arecacaceae）在埃及生长，留下浪费产品。uce compounds with anti-and anti-inflammatory activities.
MATERIALS AND METHODS: Chromatographic workup ofaqueous methanol extract derived from fibrous mesh and fruit bunch (without fruit) afforded a new sesquiterpene lactone derivative, phodactolide A (), along with ten known compounds （），主要被识别为多酚。基于质量和1D/2D NMR光谱法明确阐明了化学结构。所有孤立的化合物均评估其活性，以抗肉汤微孔稀释法，而克拉霉素作为阳性对照。 The anti-inflammatory response of isolated compounds was evaluated by inhibiting cyclooxygenase-2 enzyme using TMPD Assay followed by anstudy to validate their mechanism of action using celecoxib as a standard drug.
RESULTS: Compounds,andexhibited potent anti-activity with MIC values范围为0.48至1.95 µg/m与克拉霉素相当或更有效的L。对于COX-2抑制测定，Andreveal的有希望的活动，ICVALUE分别为1.04、0.65和0.45μg/ml。 These results were verified by molecular docking studies, where,andshowed the best interactions with key amino acid residues of COX-2 active site.
CONCLUSION: The present study characterizes a new sesquiterpene lactone and recommendsandfor futurestudies as plausible anti-ulcer补救措施。