对用坎波草药治疗的肝脏疾病的临床和药理研究。
摘要来源:
phytother res。 2007年9月; 21(9):895-7。 PMID: 11154048“> 11154048 Furuya
摘要:
丙型肝炎病毒(HCV)感染经常引起慢性肝炎,这与肝硬化和肝细胞癌的发展有关。 Most physicians who practice Kampo medicine in Japan have observed that Kampo medicine can be as effective as interferon therapy in the treatment of chronic hepatitis C. In the present study, to evaluate the effect of Kampo medicine on chronic hepatitis C, clinical treatment was assessed in short-term and long-term study, and it was shown that ninjin-yoei-to (Formula ginseng compositae: TJ-108) was very effective.因此,要找到最活跃的草药comp使用体外HCV感染模型筛选了特定于TJ-108的TJ-108在HCV处理HCV,柑橘unshiu Peel,Schisandra Fruit和Polygala root的治疗中。在三种草药中,发现Schisandra水果是最活跃的。在下一步中,使用具有Molt-4细胞的体外模型和免疫学诱导的急性肝衰竭的动物模型,研究了Schisandra果实的活性成分Gomisin A。 It is concluded that the therapeutic effect of TJ-108 on chronic hepatitis C is from the inhibitory effect on HCV infection, and also from the protective effect on immunological hepatopathy of Schisandra Fruit and its lignan component, Gomisin A.