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Abstract Title:The Effects of Hydro-Alcoholic Extract of Fenugreek Seeds on the Lipid Profile and Oxidative果糖喂养大鼠的应力。
抽象来源:
j obes metab综合症。 2020年9月30日; 29(3):198-207。 PMID: 32883888“> 32883888 Mohamadi,Mehdi Mahmoodi,Soudeh Khanamani Falahati-Pour,Mohammad Reza Hajizadeh
文章隶属关系:Maryam Mohammad-Sadeghipour
摘要
临床疾病会导致氧化应激增加。该综合征患者有糖尿病和心血管疾病的风险。瑟尔。 (胡芦巴)植物有许多疗法综合作用,包括抗糖尿病和抗氧化剂。 The present study aimed to investigate the effects of the hydro-alcoholic extract of fenugreek seeds (HEFS) on dyslipidemia and oxidative stress due to high-fructose diet-induced MetS.
Methods: In this experimental study, to induce MetS, animals received water containing 20% fructose for 8周。诱导MetS后,将48只男性Wistar大鼠(200-250 g)随机分为六组。 HEF以100和200 mg/kg口服的剂量对动物进行4周。收集动物血液样本以测量禁食血浆葡萄糖(FPG),总胆固醇(TC),高密度脂蛋白胆固醇(HDL-C)的生化和抗氧化参数过氧化物酶(GPX),过氧化氢酶(CAT)和总抗氧化能力(TAC)。
结果: 研究结果表明,与对照组相比,HEFS暴露组的FPG,TC,LDL-C,TG和MDA的血清水平显着降低(<0.05)。 Also, significant increases in HDL-C, GPX, CAT, and TAC levels (<0.05) were observed.
Conclusion: Our results revealed that treatment with HEFS increases the levels of antioxidant enzymes, decreases FPG level, and at the same time, modifies the lipid profile in大都会。因此,HEF可能有助于减轻这种疾病的某些慢性并发症的风险。