摘要标题:
来自椰子的抗真菌肽。
摘要来源:
肽。 2005年12月; 26(12):2392-6。 PMID: 16308082
摘要作者(s) Agricultural University and State Key Laboratory of Agrobiotechnology, Beijing, China.Abstract:A chromatographic procedure consisting of ion exchange chromatography on DEAE-cellulose, affinity chromatography on Affi-gel blue gel, ion exchange chromatography on CM-cellulose, and gel filtration by fast performance liquid chromatography on Supedex 75 was utilized to isolate a 10来自椰子肉的KDA抗真菌肽。该肽在Deae-Clulose上未经吸附,但在Affi-Gel Blue Gel和CM-纤维素上吸附。它表现出抗真菌活性,抗真菌性氧体,霉菌磷酸菌和Physalospora piricola。 IC50 VA其抑制活性对蛛网膜菌和HIV-1逆转录酶活性的菌丝菌活性的理论分别为1.2和52.5 microm。