新生儿高脂肪纤维血症的绿灯发射二极管光疗:随机对照试验。
摘要来源:
pediatr int。 2019年5月; 61(5):465-470。 EPUB 2019 5月20日。PMID: 30838731 30838731 Makoto Arioka,Kohichiroh nii,Megumi takahashi,Satoshi Yamato,Takaaki Sadamura,Wataru Jinnai,Akiko Nakano,Susumu Itoh Itoh
文章: 新生儿高胆红素血症光疗中的主要光化学途径是环胞脂纤维蛋白的生产和消除(胆汁或尿液),它是胆红素的结构光异构体,并且是最有效的绿光。然而,在临床环境中尚未评估绿色照明二极管(LED)光疗在美国儿科指南中受到赞扬。 We therefore compared the efficacy of green LED phototherapy and blue LED phototherapy in patients with neonatal hyperbilirubinemia.METHODS: In this prospective randomized controlled trial, neonates with hyperbilirubinemia were randomly allocated to a green LED or blue LED phototherapy group.两组都接受了24小时的光疗,并在光疗24小时之前和之后对血液进行采样。 Total serum bilirubin (TSB) was measured using enzymatic methods and bilirubin photoisomers were measured on high-performance liquid chromatography.
RESULTS: Thirty-four infants were randomized (green, n = 16; blue, n = 18).蓝色LED组(P <0.01)在绿色LED组中从15.3±1.5降至13.9±1.5 mg/dL(p <0.01),从16.2±1.3升至14.5±1.7 mg/dl,在24小时后,蓝色LED组(P <0.01)。没有意义两组之间光疗后的TSB降低中发现了差异。
结论: