饮食燕麦蛋白对高胆固醇血症仓鼠胆固醇代谢的影响。
摘要来源:
j sci food Agric。 2016年3月15日; 96(4):1396-401。 EPUB 2015年5月21日。PMID: 25913820“> 25913820 Qiu, Liya Liu, Kui Zhong, Sumei Zhou
Article Affiliation:Li-Tao Tong
Abstract:BACKGROUND: The aim of present study was to investigate the hypocholesterolaemic effects of oat proteins (OP) in hamsters fed with a hypercholesterolaemic diet. The hamsters were divided into five groups and fed with the experimental diets containing oat, OP, oatβ-glucan (OG), or OP+OG for 30 days.
RESULTS: OP and the OG significantly lowered the concentrations of plasma low-density lipoprotein-cholesterol and livER总胆固醇(TC),并增加了粪便胆汁酸和TC的排泄。 OP+OG组中的血浆和肝TC明显低于OP或OG组的血浆TC。 Both OP and OG increased the activity of liver cholesterol 7α-hydroxylase (CYP7A1), while its activity in the OP+OG group was strongly increased compared with the OP or OG groups.
CONCLUSION: These results indicated that dietary OP could improve hypercholesterolaemia, while dietary OP and OG在一起将具有更好的降血胆脂脂效应。