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Abstract Title:Regulatory/modulatory effect of prune essence concentrate on intestinal function and blood脂质。
摘要来源:
Pharm Biol。 2017年12月; 55(1):974-979。 PMID: 28164731 Yi-Chun Han,You-Cheng Shen,Oksana Golovinskaia,Kamesh Venkatakrishnan,Chin-Kun Wang
文章隶属关系:hui-fang chiu
摘要:
objective:abject: 这个position> ED,随机研究被构架以检查修剪肠子功能和脂质功能和脂质特征的有益活性。 (consume 50 mL of simulated prune drink), PEC I (consume 50 mL of PEC/day) and PEC II (consume 100 mL of PEC/day) for 4 weeks with 2 weeks of follow-up without PEC consumption.
RESULTS: Intake of PEC (I and II) for 4 weeks substantially ameliorated (p <0.05)双歧杆菌属的菌落数。 (1.18-和1.19倍)和乳杆菌属。 (1.07-和1.16倍),但明显降低(p <0.05)灌注梭状芽胞杆菌的菌落数(5.97和8.35%)和大肠杆菌(6.25和9.38%)。同时,总胆固醇(TC; 5。90和6.99%)水平和LDL-C(6.68和6.53%)显着降低(p <0.05),但其他脂质参数没有变化。 Whereas, the antioxidant capacity was also concomitantly elevated (p < 0.05) upon administration with PEC.
DISCUSSION AND CONCLUSION: Overall, the results suggest that the use of PEC may positively regulate the intestinal microflora and thereby effectively lower the TC levels and thus act as a hypocholesterolemic代理。