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Abstract Title:Impact of daily Chlorella consumption on serum lipid and carotenoid profiles in mildly高胆固醇血症成年人：一项双盲，随机，安慰剂对照的研究。
摘要来源：
Nutr J. 2014年6月11日; 13：57。 EPUB 2014年6月11日。PMID： 24920270“> 24920270 Kim，Ji Yeon Kim，Sung赢得了权，Oran Kwon
文章隶属关系：na hee ryu
摘要：
背景： cardim cholesterol的高水平被认为是一种主要风险因素。进行了一项双盲，随机，安慰剂对照试验，以测试每天摄入小球藻的假设可以改善血清lipid profile through enhancement of serum carotenoid concentration in mildly hypercholesterolemic subjects.
METHODS: Eligible subjects (n = 63) were randomized to either Chlorella (5 g/day) or placebo for a double-blinded trial with a 2-week lead-in period and a 4-week intervention period. Serum triglycerides, total cholesterol, lipoproteins, apolipoproteins and carotenoids were assessed at the beginning and the end of the trial.
RESULTS: Compared with the control group, the Chlorella group exhibited remarkable changes in total cholesterol (Chlorella -1.6%; placebo 0.03％; p = 0.036），甘油三酸酯（小球藻-10.3％;安慰剂11.9％; p = 0.002），叶黄素/Zeaxanthin（Chlorella 89.6％;安慰剂-1.7％; p <0.0001）;通过非常低密度脂蛋白凝乳的显着降低支持血清脂质的改善Terol（小球藻-11％；安慰剂11.8％; P = 0.006），载脂蛋白B（小球藻-1.5％；安慰剂1.7％； P = 0.044），非高密度脂蛋白（Chlorella -2.6％; lastbo -0.5％; P = 0.032），和高密度的Liglely/trlore蛋白; 0.0.5％； -9.5％； p = 0.023），表明小球藻对饮食和内源性脂质的肠道吸收产生抑制作用。 Further, the changes of serum lipids appeared to be associated with the changes of serum carotenoids.
CONCLUSION: Daily consumption of Chlorella supplements provided the potential of health benefits reducing serum lipid risk factors, mainly triglycerides and total cholesterol, in mildly hypercholesterolemic subjects.效果与类胡萝卜素的消耗有关。
试验注册： 谁国际临床试验注册表kct0000259。