Triton WR-1339中凤凰菌种子(日期)提取物和高脂饮食诱导大鼠的高脂血症的影响:与辛伐他汀的比较。
摘要来源:摘要来源:
j et nnopharmacol。 2020年9月15日; 259:112961。 EPUB 2020年5月11日。PMID: 32423881 32423881 Abdelbasset Hmidani,Bouchra Bourkhis,Tarik Kouya,Hicham Harnafi,Younes Filali-Zegzouti,Chakib Alem
文章隶属关系:eimad dine dine tariq bouhlali Date seeds are widely used in Moroccan traditional medicine for treating obesity and related diseases.
AIM OF THE STUDY: Two date seed varieties (Jihel and Majhoul) were assessed for their phenolic profile and lipid-lowering activity.
材料和方法: 使用HPLC-DAD。Triton-WR-1339和高脂饮食(HFD)诱导的高脂症大鼠确定多酚曲线,用于评估使用日期种子提取物的低甲脂式症状。 analyser.
RESULTS: Rutin, quercetin, p-coumaric and caffeic acids were the most prevalent chemical among the analysed phenolic compounds. Serum lipids: Total cholesterol, triglycerides, low-density lipoprotein-cholesterol were lowered and high-density在Triton WR1339诱导的实验大鼠中诱发的高脂糖尿病(在200 mg/kg)中,这些提取物(在200 mg/kg时)在Triton WR1339诱导的高脂血症中,脂蛋白 - 胆固醇增加。脂蛋白 - 胆固醇水平和动脉粥样硬化指数,而血清HDL-C则增加了。此外,补充日期提取物可有效防止体重增加。
结论: 这些发现暗示了高脂肪症和动脉粥样硬化预防Jihel和Majhel and Magh and Magh date date date date seeds。