母乳中的脂肪酸和婴儿期特应性湿疹和过敏症的发育。
摘要来源:
emovening Sci Technol。 2010年2月15日; 44(4):1458-63。 PMID: 20659079
atbracter(s) Snijders,M Huber,R Van Ree,A PSimões-Wüst,P C Dagnelie,P A Van den Brandt 文章文章隶属关系:Maastricht University/Caphri公共卫生与初级保健学院,荷兰Maastricht。 class =“ sub_abstract_label”>背景: 越来越多的特应性疾病患病率的解释之一是N-3脂肪酸的相对低围产期供应。但是,这不能解释全脂脂肪的保护作用在某些研究中观察到的母乳中的乳制品或高水平的母乳中的酸性酸。 We evaluated the role of perinatal supply of fatty acids in the early development of atopic eczema and allergic sensitisation.
METHODS: Fatty acids, including n-3 long-chain polyunsaturated fatty acids (LCPs) as well as ruminant fatty acids (rumenic acid, CIS-9,Trans-11-C18:2共轭亚油酸和疫苗酸,Trans-11-C18:1),在荷兰的Koala出生同龄人研究中的310对母乳中确定了在310个母乳中采样的母乳。 Children were followed for atopic outcomes until 2 years of age.
RESULTS: Higher concentrations of n-3 LCPs as well as ruminant fatty acids were associated with lower risk of (1) parent-reported eczema, (2) atopic dermatitis (UK Working Party criteria), and (3) sensitisation at age 1年(如规格所揭示FIC血清IgE水平为牛奶,母鸡和/或花生)。在多变量的逻辑回归分析中,发现母乳中反刍脂肪酸浓度与特应结局之间的反相关性与N-3 LCP无关。
结论: