从达马斯克玫瑰的花卉酿酒厂分离的2-苯基乙醇的血管脱落性能（Rosa Damascena Mill。）及其可能的机制。
摘要来源：
j ethnopharmacol。 2023年9月15日； 313：116603。 EPUB 2023 5月4日。PMID： 37149069 Swati Singh, Divya Mishra, Poonam Rani, Debabrata Chanda, Ram Swaroop Verma
Article Affiliation:Munmun Kumar Singh
Abstract:ETHNOBOTANICAL RELEVANCE: Rosa damascena Mill. (Rosaceae), commonly known as damask rose, is an ancient medicinal and perfumery plant used in Traditional Unani Medicine due to various therapeutic effects, including cardiovascular benefits.
AIM OF THE STUDY: This study aimed to evaluate the vasorelaxant effect of the 2-phenyl ethyl alcohol (PEA) isolated from the spent flowers of R. damascena which remain after the extraction of essential oil.
MATERIALS AND METHODS: The freshly collected flowers of R. damascena were hydro-distilled in a Clevengers type apparatus to extract the rose essential oil (REO).删除REO后，收集了花水的水呈丝酸酯并用有机溶剂提取，以产生花费的液压水分提取物（SFHE），该水溶剂提取物（SFHE）通过柱色谱法进一步纯化。 SFHE及其分离株的特征是气相色谱（GC-FID），气相色谱 - 质量光谱法（GC-MS）和核磁共振（NMR）技术。评估了从SFHE分离的豌豆在大鼠主动脉（如大鼠主动脉和诸如肠系膜动脉）等耐药血管等导管血管中评估了血管瘤的反应。 PEA的初步筛查是在用苯肾/U46619预先指示的主动脉制备中进行的。Further, a concentration-dependent relaxation response to PEA has been elicited in both endothelium-intact and endothelium-denuded arterial rings, and the mode of action was explored.
RESULTS: The SFHE revealed the presence of PEA as the main constituent (89.36%), which was further purified列色谱法的纯度为95.0％。豌豆在大鼠主动脉等导管血管和肠系膜动脉等电阻血管中表现出有效的血管延缓反应。放松反应是介导的，而无需任何血管内皮。此外，发现对这些血管中豌豆诱导的松弛反应的主要目标是
结论： R. amancena的花朵r.ant> r. amancena的花朵，可用于提取pea的R. amancena的花朵，可用于提取pea，可用于提取pea。豌豆在主动脉和肠系膜动脉并显示出对高血压的草药发育的希望。