发酵脱脂骆驼(Camelus dromedarius)牛奶对自发性高血压大鼠的降压作用。
摘要来源:
Nutr Hosp。 2017年3月30日; 34(2):416-421。 EPUB 2017 3月30日。PMID: 28421799 28421799 Abdullrahman s al-Khalifah
文章隶属关系:Mohammed Yahya
摘要:
背景: 高血压>高血压是世界上最常见的疾病,因此,预防疾病中的疾病中有一定的疾病。 Milk contains bioactive peptides released during milk fermentation which lead to exhibit angiotensin I converting enzyme (ACE) inhibitory.
OBJECTIVE: The aim of this study was to investigate the antihypertensive effect of fermented skim camel milk on rats并将其与未发酵的脱脂骆驼奶作为对照。
方法: 发酵脱脂型骆驼牛奶的抗高血压效应在36个男性自发性高血压大鼠(SHR)中(短期)和(短期)(使用(短期)(长期)(240)((使用)(24))(240)(240)(240)(240)(240)(240)(240)(( mg/kg体重)。血管紧张素还使用ACE试剂盒进行转化酶(ACE)活性。
结果: 在短期内(24小时)的自发性高压量(SHR)的血压(收缩压和舒张性)的血压(收缩压和舒张性)(24小时)的1200 mg/k g gim/kg cam cam/k. (p <0.05)分别从22至36 mmHg和28至32 mmHg,在给药后四个小时和八个小时。另一方面,长期(20天)发酵的脱脂骆驼牛奶的血压降低并影响心率(节拍/分钟)。收缩期(41 mmHg)和Diastoli的最低记录C血压(19 mmHg)的剂量为1200 mg/kg的体重,在给药15天后发酵奶酪奶牛。 Likewise, ACE activity in plasma of SHR administered fermented skim camel milk decreased significantly (p<0.05) compared with the control group.
CONCLUSION: The hypotensive effect of fermented skim camel milk by L. helveticus and S. thermophillus in SHR rats depends on the high dose of短期和长期发酵的脱脂骆驼奶。用发酵的脱脂骆驼牛奶清晰地抑制ACE活性。