[Provens®在青光眼和眼高血压治疗中]。
摘要来源：
cesk slov oftalmol。 2015; 71（6）：288-92。 PMID： 26782917 Pešková, P Mlčák, Z Fryšák, K Marešová, J Zapletalová
Article Affiliation:M Karhanová
Abstract:OBJECTIVE: To assess the effect of the ProVens® dietary supplement administration on intraocular pressure in patients with glaucoma and眼高血压。
材料和方法： 试验中包括的患者每天给予Provens®饮食补充剂。一种Provens®片剂包含：50毫克的海洋松树皮提取物，100毫克的绿茶提取物和3毫克的蓝莓提取物。 MainProvens®成分是树皮O的素蛋白蛋白f海上松树Pinus Pinaster，来自绿茶的多酚，蓝莓的Andanthocyanins。试验中包括的患者总数为46。在这些患者中，有35例患者的无症状眼高血压和11例患者接受了前列腺素类似物治疗的开角青光眼。 Intraocular pressure was measured by applanation tonometry in the beginning of the trial, after one month, and after three months of their inclusion in the trial, always at the same time of the day.
RESULTS: In the group of patients with ocular hypertension, there was a statistically significant reduction in the intraocular pressure from the baseline values of在三个月内（p <0.0001），24.2±2.1 mm hg至20.9±2.5 mm Hg。在一组敞开角质青光眼的患者中，从基线值的18.4±3.2 mm hg到17.0±±17.0±的统计学显着降低。自产品施用以来三个月内的3.1 mm Hg（p = 0.022）。在比较两组时，我们观察到眼部高血压患者组的眼内压（P = 0.0001）的降低明显更高。 In the whole group, no adverse effects were reported during the intake of this dietary supplement.
CONCLUSION: Intake of the ProVens® dietary supplement containing proanthocyanins from the bark of the maritime pine tree Pinus pinaster together with a mixture of herbal antioxidants appears to be one of the methods of how to improve the control of intraocular pressure, particularly in patients with ocular hypertension.
KEY WORDS: glaucoma, ocular hypertension, ProVens®, proanthocyanins, antioxidants, maritime pine bark extract.