中国的新鲜水果消耗和主要的心血管疾病。
摘要来源:
n Engl J Med。 2016年4月7日; 374(14):1332-43。 PMID: 27050205”> 27050205
摘要作者: Bian,Paul Sherliker,Haiyan Gao,Yiping Chen,Ling Yang,Junshi Chen,Shanqing Wang,Shanqing Wang,Ranran DU,Ranran DU,Hua Su,Hua Su,Rory Collins,Rory Collins,Richard Peto,Zhengming Chen,文章附属: In Western populations, a higher level of fruit consumption has been associated with a lower risk of cardiovascular disease, but little is known about such associations in China, where the consumption level is low and rates of stroke are high.METHODS: Between 2004 and 2008, we recruited 512,891成人,30至79岁,来自中国的10个不同地区。在320万人的随访期间,患有心血管疾病的5173例死亡,2551例主要冠状动脉事件(致命或非致命事件),14,579例缺血性中风和3523例未记录的451,665参与者中没有患有心脏病患者或静脉病史的451,665参与者中的3523例脑出血。 Cox回归产生的调整后危险比与疾病率有关。
结果: 总体而言,每天有18.0%的参与者每天消耗新鲜水果。与从未或很少消耗新鲜水果的参与者(“非消费”类别)相比,每天吃新鲜水果的人的收缩压较低(4.0 mm Hg)和血糖水平(每升9.0 mg [9.0 mg [9.0 mg])(两种比较的趋势p <0.001)。调整后的日常消费危险比与非消费的危险比n为0.60(95%的置信区间[CI],0.54至0.67),为0.66(95%CI,0.58至0.75),0.75(95%CI,0.72至0.79),以及0.64(95%CI,0.56至0.56至0.74),分别为corrone and cororn and Corornary inscor and Corrone and inscor and cororn and inscor and corornary and s。每个结果的发生率与消耗的新鲜水果量之间存在很强的对数线性剂量反应关系。 These associations were similar across the 10 study regions and in subgroups of participants defined by baseline characteristics.
CONCLUSIONS: Among Chinese adults, a higher level of fruit consumption was associated with lower blood pressure and blood glucose levels and, largely independent of these and other dietary and nondietary factors, with significantly lower risks of major心血管疾病。 (由Wellcome Trust和其他人资助。)。