Brevis dm9218通过肌苷降解和肠道营养不良的操纵来改善果糖诱导的高尿素血症。
摘要来源:
营养。 2019年6月; 62:63-73。 EPUB 2018 11月26日。PMID: 30852460 30852460 刘,小韦,刘,乔伊·朱,韩马,彭格扬恩,吉里·尤恩,jieli yuan,明li
文章隶属关系:haina wang
摘要:
RESULTS: Our results indicated that DM9218 could decrease serum UA level and hepatic xanthine oxidase activity in果糖喂养的小鼠。它可以防止高果糖诱导的肝损伤并通过降解内因降解UA积累。 DM9218对高果糖诱导的肠道营养不良的调节作用导致增强intestinal barrier function and reduction of liver lipopolysaccharide, which was closely correlated with the down-regulation of inflammatory cytokine-stimulated xanthine oxidase expression and activity.
CONCLUSIONS: Lactobacillus brevis DM9218 is a probiotic strain with the potential to改善果糖诱导的高尿酸血症。