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Abstract Title:Effect of selenium on anti-Tg antibody in patients with autoimmune hypothyroidism: A随机对照试验。
摘要来源:
caspian J Intern Med。 2024; 15(2):340-346。 PMID: 38807724“> 38807724 Beizae,Hossein Ayatollahi,Maryam Emadzadeh,Mehrdad Sarabi,Nikoo Saeedi,Negar nekooei
文章隶属关系:mina akbarirad
摘要:
方法: 在此双叶子随机对立的TRIAL,两组72例自身免疫性甲状腺功能减退患者被随机分配;一组接受左甲状腺素(LT4)和口服硒,另一组用LT4给予安慰剂。 Anti-Tg antibody, free T4, anti-TPO antibody, and TSH were identified in both groups before the treatment and also 3 months after treatment and analysis of data was done by SPSS software.
RESULTS: After the intervention, the average amount of anti-Tg antibody decreased in both of the groups, and this decrease was干预组明显更大(p = 0.03)。在干预组中,干预后TSH水平降低(p <0.05),干预后的自由T4水平升高(p <0.05);与安慰剂相比LY降低了抗TG抗体的水平,并显着增加了自由T4水平。同样,与对照组相比,TSH的水平有更大的降低。