人参:一种有前途的炎症性肠病治疗方法。
摘要来源:
PharmacolRep。2021Jan 19. Epub 2021 Jan 19. pmid:33462754
Abstract Author(s):Zengping Kang, Youbao Zhonga, Tiantian Wu, Jiaqi Huang, Haimei Zhao, Duanyong Liu
Article隶属关系:Zengping Kang
摘要:炎症性肠病(IBD)是一种由免疫疾病介导的自身免疫性疾病,被称为健康组织一词最难治性疾病之一。在过去的半个世纪中,它的发病率在全球范围内稳步增长。环境,遗传,感染和免疫因子是IBD发病机理的组成部分。在过去的2000年中,Ginseng通常被称为草药之王,在许多国家都被消耗掉。它的活性成分人参作为人参最突出的皂苷,具有广泛的药物学术效应。 Recent studies have confirmed that the active components of Panax ginseng have anti-inflammatory and immunomodulatory effects on IBD, including regulating the balance of immune cells, inhibiting the expression of cytokines, as well as activating Toll-like receptor 4, Nuclear factor-kappa B (NF-κB), nucleotide-binding oligomerization domain-like receptor (NLRP),有丝分裂原激活的蛋白激酶信号传导等等。积累的证据表明,在IBD预防和治疗中,人参皂苷可能是一种潜在的新型治疗药物或健康产品添加剂。