评估流体雌激素和抗炎活性的水力 - 乙醇提取物和欧芹的多酚部分(Petroselinum sativum hoffm。)。
摘要来源:摘要来源:
2020年8月22日; 265:113290。 EPUB 2020 8月22日。PMID: 32841696 32841696 Ez-Zahra Amrati,Francesca di Cristo,Amal Amaghnouje,Andrey Grafov,Nabil Boucetta,Amina Bari,Amina Bari,Dalila Bousta
文章隶属关系:Meryem Slighoua 以来,自时间黎明以来,药用和芳香植物(AMP)代表了人类的宝贵遗产,尤其是在发展中国家,他们在传统药典中利用自己的美德来应对糖尿病,肾结石,溃疡,溃疡和消化疾病等健康问题。石油公司um sativum hoffm。属于apiaceae家族。 It is traditionally used to treat arterial hypertension, diabetes, cardiac disease, renal disease, and recently reported as a plant endowed with a female anti-infertility effect.
AIM OF THE STUDY: This study aims to evaluate the in vivo effect of hydro-ethanolic extract and polyphenols of petroselinum sativum hoffm。在胆固醇,蛋白质和雌激素水平上,并表征了多酚部分的化学组成。此外,还研究了测试提取物的急性毒性和抗炎活性。
材料和方法: 使用高效液体液体液体液体级别的化学级数确定了与二极管液体级别的液态液体分数的化学组成。首先,通过每天测量动物体重四个星期来进行包括亚急性毒性在内的毒理学研究。毕竟还检查了ARDS,肝脏和肾脏的组织病理学检查以及ASAT和ALAT的血清测定法。接下来,对石油饱满的水力 - 乙醇提取物和多酚的急性体内抗炎研究。进行与吲哚美辛进行。 Furthermore, we evaluated the estrogenic effect of its hydro-ethanolic extract and the polyphenolic fraction following biochemical assays for the determination of proteins, cholesterol and estrogen levels.
RESULTS: The results revealed the presence of some phenolic compounds mainly ferulic acid, gallic acid和槲皮素。 petroselinum sativum hoffm。 extracts also showed no evidence of hepatotoxicity nor nephrotoxicity, with remarkable anti-inflammatory activity, as well as a significant estrogenic effect compared to negative control.
CONCLUSION: This study provides a scope of the potential use of PetrosElinum Sativum Hoffm。在反对女性不育问题中提取的提取物。