细胞因子。 2019年11月15日; 126:154922。 EPUB 2019 11月15日。pmid: 31739218> 31739218 Amir Hadi, Ehsan Ghaedi, Micheal E Symonds, Maryam Miraghajani, Parisa Javadian
Article Affiliation:Moein Askarpour
Abstract:OBJECTIVES: The rationale for the current study was to evaluate the efficacy of flaxseed supplementation on成人中重要的粘附分子和炎症细胞因子。
方法:
结果: 40个合格的RCT,包括2520参与者在内。 The results of the meta-analysis revealed flaxseed supplementation reduced the concentrations of CRP (WMD = -0.387 mg/L; 95% CI: -0.653, -0.121, p = 0.004), IL-6 (WMD = -0.154 pg/Ml; 95% CI: -0.299, -0.010, p = 0.036),和VCAM-1(WMD = -22.809NG/ML; 95%CI:-41.498,-4.120,-4.120,p = 0.017),但对TNF-α没有显着影响(WMD = -0.077pg/ml; 95%CI:95%CI:-0.317,0.163,0.163,p = 0.530) (WMD = -8.610ng/ml; 95%CI:-21.936,4.716,p = 0.205)和E-selectin (WMD = -1.427 ng/ml; 95% CI: -4.074, 1.22, p = 0.291).
CONCLUSIONS: These findings showed that flaxseed supplementation may improve some circulating concentrations of specific adhesion molecules and inflammatory细胞因子。但是,需要精心设计的试验来确认非显着和/或模棱两可的发现的范围。